Melanotan-1
A metabolically stabilized α-MSH analog studied as a selective MC1R agonist in melanogenesis research.
Research Overview
Melanotan-1 (afamelanotide) is a tridecapeptide analog of α-melanocyte-stimulating hormone carrying two substitutions — norleucine at position 4 and D-phenylalanine at position 7 — which the literature associates with markedly increased resistance to enzymatic degradation relative to native α-MSH.
Research characterises it as an agonist at the melanocortin-1 receptor, where receptor binding is studied for cAMP-mediated upregulation of tyrosinase and subsequent eumelanin synthesis in melanocyte models.
Specifications
| Compound | Melanotan-1 (CAS 75921-69-6) |
| Classification | Regenerative research compound |
| Molecular weight | 1,646.85 g/mol |
| Sequence / Form | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ |
| Purity | ≥98% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
Quality Documentation
Every released lot is supported by quality-control documentation. Certificate access is presented by compound and lot where available. Cold-chain shipping is available where required; inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
Research Use Only
This product is offered strictly for laboratory research use. It is not a drug, food, cosmetic, supplement, or consumer product, and is not intended for human or veterinary use.
