01At a Glance
| Compound | AICAR (Acadesine; AICA riboside) |
| Classification | Mitochondrial research compound |
| Molecular weight | 258.23 g/mol |
| Sequence / Form | Nucleoside (non-peptide) |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
AICAR is a nucleoside that is converted intracellularly to ZMP, an AMP mimetic that directly activates AMP-activated protein kinase (AMPK). Through AMPK it is studied for effects on glucose uptake (GLUT4 translocation), fatty-acid oxidation, and mitochondrial biogenesis (PGC-1α).
It is a classic exercise-mimetic research tool in metabolic studies. Note: AICAR is a small-molecule nucleoside, not a peptide.
Research framing only · No human-use claims
03Research Context
- AMPK-activation and energy-sensing assays
- Glucose-uptake and GLUT4 translocation models
- Mitochondrial-biogenesis (PGC-1α) research
- Exercise-mimetic metabolic studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is AICAR?
AICAR is a nucleoside that activates AMPK, studied for glucose metabolism, fatty-acid oxidation, and mitochondrial biogenesis as an exercise-mimetic research tool. It is sold for research use only.
Is AICAR a peptide?
No — AICAR is a small-molecule nucleoside (AICA riboside), not a peptide, supplied as a research reagent.
What is AICAR's molecular weight?
AICAR has a molecular weight of approximately 258.23 g/mol and CAS number 2627-69-2.
How should AICAR be stored?
AICAR ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is AICAR approved for human use?
No. AICAR is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is AICAR tested at Ethos Bio?
Every AICAR lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.