ARA-290
An erythropoietin-derived peptide studied for innate-repair-receptor signaling.
01At a Glance
| Compound | ARA-290 (Cibinetide) |
| Classification | Regenerative research compound |
| Molecular weight | 1,258.42 g/mol |
| Sequence / Form | 11-aa EPO helix-B fragment |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from the helix-B region of erythropoietin. It is studied as a selective agonist of the innate repair receptor — a heterocomplex of the EPO receptor and the β-common receptor (CD131) — associated with tissue protection and anti-inflammatory signaling.
Importantly, it is non-erythropoietic, separating tissue-protective signaling from red-blood-cell effects, which makes it a focused research tool.
Research framing only · No human-use claims
03Research Context
- Innate-repair-receptor (EPOR/CD131) signaling assays
- Tissue-protection and anti-inflammatory models
- Neuropathy and small-fiber research
- Non-erythropoietic EPO-signaling studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is ARA-290?
ARA-290 (cibinetide) is an erythropoietin-derived 11-amino-acid peptide studied for innate-repair-receptor signaling and tissue protection in research models. It is sold for research use only.
Is ARA-290 erythropoietic?
No — ARA-290 is studied as a non-erythropoietic peptide, meaning it targets tissue-protective EPO signaling without the red-blood-cell-stimulating activity of erythropoietin.
What is ARA-290's molecular weight?
ARA-290 has an approximate molecular weight of 1,258.42 g/mol and CAS number 1208243-50-8.
How should ARA-290 be stored?
ARA-290 ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is ARA-290 approved for human use?
No. ARA-290 is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is ARA-290 tested at Ethos Bio?
Every ARA-290 lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.