ARA-290
An erythropoietin-derived peptide studied for innate-repair-receptor signaling.
01At a Glance
| Compound | ARA-290 |
| Also known as | Cibinetide |
| CAS Number | 1208243-50-8 |
| Molecular Weight | 1,258.42 g/mol |
| Sequence / Form | 11-aa EPO helix-B fragment |
| Classification | Regenerative research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from the helix-B region of erythropoietin. It is studied as a selective agonist of the innate repair receptor — a heterocomplex of the EPO receptor and the β-common receptor (CD131) — associated with tissue protection and anti-inflammatory signaling.
Importantly, it is non-erythropoietic, separating tissue-protective signaling from red-blood-cell effects, which makes it a focused research tool.
03Research Applications
- 01Innate-repair-receptor (EPOR/CD131) signaling assays
- 02Tissue-protection and anti-inflammatory models
- 03Neuropathy and small-fiber research
- 04Non-erythropoietic EPO-signaling studies
04Purity & Verification
Every Ethos Bio lot of ARA-290 is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the ARA-290 Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is ARA-290?
ARA-290 (cibinetide) is an erythropoietin-derived 11-amino-acid peptide studied for innate-repair-receptor signaling and tissue protection in research models. It is sold for research use only.
Is ARA-290 erythropoietic?
No — ARA-290 is studied as a non-erythropoietic peptide, meaning it targets tissue-protective EPO signaling without the red-blood-cell-stimulating activity of erythropoietin.
What is ARA-290's molecular weight?
ARA-290 has an approximate molecular weight of 1,258.42 g/mol and CAS number 1208243-50-8.