BPC-157
A synthetic gastric pentadecapeptide widely studied for angiogenic and cytoprotective signaling.
01At a Glance
| Compound | BPC-157 |
| Also known as | Body Protection Compound 157; PL 14736 |
| CAS Number | 137525-51-0 |
| Molecular Weight | 1,419.5 g/mol |
| Sequence / Form | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Classification | Regenerative research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
BPC-157 is a stable 15-amino-acid sequence derived from a protective protein found in human gastric juice. In research models it is most associated with the VEGFR2–Akt–eNOS signaling axis, where it has been reported to upregulate vascular endothelial growth factor receptor 2 and promote angiogenesis in endothelial cell assays.
Additional published work examines its interaction with the nitric oxide (NO) system and the FAK–paxillin pathway governing fibroblast and tendon-cell migration, as well as modulation of growth-factor expression. These pathways are the focus of in-vitro and animal-model investigation only.
03Research Applications
- 01Angiogenesis and endothelial tube-formation assays (VEGFR2 signaling)
- 02Tendon-, ligament-, and fibroblast-migration models
- 03Gastrointestinal epithelial and mucosal-integrity research
- 04Nitric-oxide pathway and vascular-tone studies
04Purity & Verification
Every Ethos Bio lot of BPC-157 is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the BPC-157 Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is BPC-157 in research terms?
BPC-157 is a synthetic 15-amino-acid peptide derived from a sequence in human gastric protein. It is studied in vitro and in animal models for angiogenic (VEGFR2) and cell-migration signaling. It is sold for research use only and is not for human consumption.
What is the molecular weight and CAS number of BPC-157?
BPC-157 has a molecular weight of approximately 1,419.5 g/mol and CAS number 137525-51-0.
How is BPC-157 purity verified?
Each Ethos Bio lot is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry, with a certificate of analysis documenting ≥99% purity provided per lot.