CJC-1295
A growth-hormone-releasing hormone analog studied for pulsatile GH secretion.
01At a Glance
| Compound | CJC-1295 |
| Also known as | Modified GRF 1-29 (no DAC) |
| CAS Number | 863288-34-0 |
| Molecular Weight | 3,367.8 g/mol |
| Sequence / Form | Modified GRF(1-29) |
| Classification | Endocrine research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
CJC-1295 (without DAC) is a modified analog of growth-hormone-releasing hormone (GHRH) fragment 1-29. It acts as a GHRH-receptor agonist on pituitary somatotrophs, studied for its capacity to stimulate growth-hormone release while preserving the natural pulsatile pattern.
The amino-acid substitutions improve enzymatic stability relative to native GRF. Research is confined to endocrine-signaling and pituitary-secretion models.
03Research Applications
- 01GHRH-receptor agonism and pituitary-signaling assays
- 02Pulsatile growth-hormone-secretion research
- 03GH–IGF-1 axis endocrine models
- 04Peptide-stability comparison studies
04Purity & Verification
Every Ethos Bio lot of CJC-1295 is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the CJC-1295 Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is CJC-1295?
CJC-1295 is a growth-hormone-releasing hormone (GHRH) analog studied for its effect on pulsatile growth-hormone release via the GHRH receptor in research models. It is a research-use-only compound.
What does 'no DAC' mean for CJC-1295?
'No DAC' refers to the version without the Drug Affinity Complex modification; it is also called Modified GRF 1-29 and has a shorter half-life than the DAC variant in research contexts.
What is CJC-1295's molecular weight?
CJC-1295 (no DAC) has an approximate molecular weight of 3,367.8 g/mol and CAS number 863288-34-0.