Epitalon
A synthetic tetrapeptide studied primarily for telomerase activity and chromosomal stability.
01At a Glance
| Compound | Epitalon |
| Also known as | Epithalon; Epithalamin tetrapeptide |
| CAS Number | 307297-39-8 |
| Molecular Weight | 390.39 g/mol |
| Sequence / Form | Ala-Glu-Asp-Gly (AEDG) |
| Classification | Genomic research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
Epitalon is a short Ala-Glu-Asp-Gly tetrapeptide modeled on the pineal peptide epithalamin. Its most-studied research property is induction of telomerase (hTERT) expression, with published assays reporting telomere elongation in cultured somatic cells.
Other investigations examine its role in pineal/melatonin regulation and broader gene-expression and circadian effects in aged cell populations. These are laboratory research contexts only.
03Research Applications
- 01Telomerase (hTERT) activity and telomere-length assays
- 02Cellular senescence and replicative-aging models
- 03Circadian and pineal/melatonin pathway research
- 04Gene-expression studies in aged cell lines
04Purity & Verification
Every Ethos Bio lot of Epitalon is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the Epitalon Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is Epitalon studied for?
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied in vitro for telomerase induction, telomere maintenance, and chromosomal stability in aged cell populations. It is a research-use-only compound.
Is Epitalon the same as Epithalon?
Yes — 'Epitalon' and 'Epithalon' are alternate spellings of the same Ala-Glu-Asp-Gly tetrapeptide (CAS 307297-39-8).
What is Epitalon's molecular weight?
Epitalon has a molecular weight of approximately 390.39 g/mol, making it one of the smallest peptides in the research catalog.