Glutathione
The endogenous tripeptide master antioxidant studied for redox and detoxification research.
01At a Glance
| Compound | Glutathione |
| Also known as | GSH; reduced glutathione |
| CAS Number | 70-18-8 |
| Molecular Weight | 307.32 g/mol |
| Sequence / Form | γ-Glu-Cys-Gly |
| Classification | Mitochondrial research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
Glutathione (GSH) is an endogenous tripeptide (γ-glutamyl-cysteinyl-glycine) and the cell's principal thiol antioxidant. Its reactive cysteine thiol neutralizes reactive oxygen species and serves as a substrate for glutathione peroxidase in redox-balance research.
It also participates in phase-II detoxification via glutathione-S-transferase conjugation, making it a core tool in oxidative-stress and detoxification studies.
03Research Applications
- 01Cellular redox-balance and thiol-chemistry assays
- 02Oxidative-stress and ROS-scavenging models
- 03Glutathione-peroxidase and -reductase research
- 04Phase-II detoxification (GST) studies
04Purity & Verification
Every Ethos Bio lot of Glutathione is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the Glutathione Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is glutathione used for in research?
Glutathione is the endogenous tripeptide master antioxidant studied for redox balance, ROS scavenging, and phase-II detoxification in research models. It is sold for research use only.
What is the structure of glutathione?
Glutathione is a tripeptide with the sequence γ-Glu-Cys-Gly, molecular weight approximately 307.32 g/mol, and CAS number 70-18-8.
Why is the cysteine residue important?
The cysteine thiol (-SH) group is the reactive center responsible for glutathione's antioxidant and conjugation chemistry studied in redox research.