IGF-1 LR3
A long-acting IGF-1 analog studied for IGF-1R signaling and cell proliferation.
01At a Glance
| Compound | IGF-1 LR3 (Long R3 IGF-1) |
| Classification | Endocrine research compound |
| Molecular weight | 9,117.7 g/mol |
| Sequence / Form | 83-aa Long Arg3 IGF-1 analog |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
IGF-1 LR3 is an 83-amino-acid analog of insulin-like growth factor 1, modified with an Arg substitution at position 3 and an N-terminal extension that reduces binding to IGF-binding proteins, prolonging its activity in research systems.
It is studied as an agonist of the IGF-1 receptor, activating PI3K/Akt and MAPK signaling associated with cell proliferation and protein synthesis in culture models.
Research framing only · No human-use claims
03Research Context
- IGF-1 receptor signaling assays
- PI3K/Akt and MAPK pathway research
- Cell-proliferation and culture-supplement models
- Myotube hypertrophy and protein-synthesis studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is IGF-1 LR3?
IGF-1 LR3 (Long R3 IGF-1) is a long-acting analog of insulin-like growth factor 1 studied for IGF-1R signaling and cell proliferation in research and cell-culture models. It is sold for research use only.
Why does IGF-1 LR3 last longer than native IGF-1?
Its structural modifications reduce binding to IGF-binding proteins, increasing free availability and prolonging activity in research systems.
What is IGF-1 LR3's molecular weight?
IGF-1 LR3 has an approximate molecular weight of 9,117.7 g/mol and CAS number 946870-92-4.
How should IGF-1 LR3 be stored?
IGF-1 LR3 ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is IGF-1 LR3 approved for human use?
No. IGF-1 LR3 is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is IGF-1 LR3 tested at Ethos Bio?
Every IGF-1 LR3 lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.