Ipamorelin
A selective ghrelin-receptor agonist studied for clean growth-hormone secretagogue activity.

01At a Glance
| Compound | Ipamorelin (NNC 26-0161) |
| Classification | Endocrine research compound |
| Molecular weight | 711.85 g/mol |
| Sequence / Form | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
Ipamorelin is a synthetic pentapeptide and selective agonist of the ghrelin receptor (GHS-R1a). In research models it stimulates growth-hormone release from the pituitary with notable selectivity — published work emphasizes minimal effect on prolactin, cortisol, and ACTH compared with earlier secretagogues.
This selectivity makes it a frequently used reference tool in GH-secretagogue specificity research.
Research framing only · No human-use claims
03Research Context
- GHS-R1a (ghrelin receptor) agonism assays
- Selective growth-hormone-secretagogue research
- Pituitary hormone-selectivity comparison models
- GH-axis endocrine studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What makes Ipamorelin selective?
In research models Ipamorelin stimulates growth-hormone release via the ghrelin receptor with minimal impact on prolactin, cortisol, and ACTH, making it a selective secretagogue tool. It is sold for research use only.
What receptor does Ipamorelin target?
Ipamorelin is an agonist of the growth-hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor.
What is Ipamorelin's molecular weight?
Ipamorelin has a molecular weight of approximately 711.85 g/mol and CAS number 170851-70-4.
How should Ipamorelin be stored?
Ipamorelin ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is Ipamorelin approved for human use?
No. Ipamorelin is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is Ipamorelin tested at Ethos Bio?
Every Ipamorelin lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.