NAD+
An essential redox coenzyme and sirtuin cofactor central to cellular energy research.
01At a Glance
| Compound | NAD+ |
| Also known as | Nicotinamide adenine dinucleotide |
| CAS Number | 53-84-9 |
| Molecular Weight | 663.43 g/mol |
| Classification | Mitochondrial research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme in redox reactions, cycling between NAD+ and NADH to shuttle electrons through central metabolism. It is the rate-limiting cofactor for the sirtuin family (SIRT1–7) of deacetylases studied in cellular-aging research.
NAD+ is also consumed by PARP enzymes during DNA-damage repair and by CD38. These intersecting pathways make it a core tool in cellular-energetics and DNA-repair research.
03Research Applications
- 01Sirtuin (SIRT1–7) activity assays
- 02Cellular redox and bioenergetics research
- 03PARP-mediated DNA-repair models
- 04NAD+ salvage-pathway and metabolism studies
04Purity & Verification
Every Ethos Bio lot of NAD+ is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the NAD+ Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is NAD+ used for in research?
NAD+ is an essential redox coenzyme and sirtuin cofactor studied in cellular energy metabolism, DNA repair (PARP), and aging-related sirtuin research. It is sold for research use only.
What is the CAS number of NAD+?
NAD+ has CAS number 53-84-9 and a molecular weight of approximately 663.43 g/mol.
How is NAD+ stored?
NAD+ is supplied as a lyophilized powder and stored cold (2–8°C, or frozen for long-term storage) to preserve stability, with a certificate of analysis provided per lot.