PT-141
A melanocortin receptor agonist studied for MC3R/MC4R signaling in research models.
01At a Glance
| Compound | PT-141 (Bremelanotide) |
| Classification | Wellness research compound |
| Molecular weight | 1,025.2 g/mol |
| Sequence / Form | Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
PT-141 (bremelanotide) is a cyclic heptapeptide analog of α-MSH that acts as an agonist at the melanocortin receptors, principally MC3R and MC4R. Research models study its central-nervous-system melanocortin-pathway signaling.
Unlike peripheral vasoactive compounds, it is investigated for receptor-mediated central signaling, which is the focus of its research literature.
Research framing only · No human-use claims
03Research Context
- Melanocortin MC3R/MC4R receptor agonism assays
- Central nervous system signaling research
- Neurobehavioral pathway models
- Melanocortin-system comparative studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is PT-141?
PT-141 (bremelanotide) is a cyclic peptide melanocortin receptor agonist studied for MC3R/MC4R signaling in research models. It is sold for research use only and is not for human consumption.
What receptors does PT-141 target?
PT-141 is studied as an agonist at the melanocortin receptors, principally MC3R and MC4R.
What is PT-141\u2019s molecular weight?
PT-141 has a molecular weight of approximately 1,025.2 g/mol and CAS number 189691-06-3.
How should PT-141 be stored?
PT-141 ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is PT-141 approved for human use?
No. PT-141 is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is PT-141 tested at Ethos Bio?
Every PT-141 lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.