PT-141
A melanocortin receptor agonist studied for MC3R/MC4R signaling in research models.
01At a Glance
| Compound | PT-141 |
| Also known as | Bremelanotide |
| CAS Number | 189691-06-3 |
| Molecular Weight | 1,025.2 g/mol |
| Sequence / Form | Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH |
| Classification | Wellness research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
PT-141 (bremelanotide) is a cyclic heptapeptide analog of α-MSH that acts as an agonist at the melanocortin receptors, principally MC3R and MC4R. Research models study its central-nervous-system melanocortin-pathway signaling.
Unlike peripheral vasoactive compounds, it is investigated for receptor-mediated central signaling, which is the focus of its research literature.
03Research Applications
- 01Melanocortin MC3R/MC4R receptor agonism assays
- 02Central nervous system signaling research
- 03Neurobehavioral pathway models
- 04Melanocortin-system comparative studies
04Purity & Verification
Every Ethos Bio lot of PT-141 is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the PT-141 Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is PT-141?
PT-141 (bremelanotide) is a cyclic peptide melanocortin receptor agonist studied for MC3R/MC4R signaling in research models. It is sold for research use only and is not for human consumption.
What receptors does PT-141 target?
PT-141 is studied as an agonist at the melanocortin receptors, principally MC3R and MC4R.
What is PT-141\u2019s molecular weight?
PT-141 has a molecular weight of approximately 1,025.2 g/mol and CAS number 189691-06-3.