R3
A triple GIP / GLP-1 / glucagon receptor agonist studied for multi-incretin metabolic signaling.
01At a Glance
| Compound | R3 (LY3437943) |
| Classification | Metabolic research compound |
| Molecular weight | 4,731.32 g/mol |
| Sequence / Form | Synthetic triple-agonist peptide |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
R3 is a synthetic triple agonist targeting the GIP, GLP-1, and glucagon receptors simultaneously. Research models investigate the combined contribution of all three pathways to glucose regulation, lipid metabolism, and energy expenditure.
The triple-receptor mechanism distinguishes it as a next-generation incretin research compound and a frequent subject of comparative agonist studies.
Research framing only · No human-use claims
03Research Context
- Triple incretin/glucagon receptor co-activation assays
- Glucose- and lipid-metabolism models
- Energy-expenditure and metabolic research
- Comparative multi-agonist studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is R3?
R3 is a synthetic triple agonist of the GIP, GLP-1, and glucagon receptors, studied for multi-incretin metabolic signaling in research models. It is sold for research use only.
How is R3 different from TZ2?
R3 is a triple agonist (GIP, GLP-1, and glucagon receptors), while TZ2 is a dual agonist (GIP and GLP-1). The added glucagon-receptor activity is the key research distinction.
What is R3\u2019s molecular weight?
R3 has a molecular weight of approximately 4,731.32 g/mol and CAS number 2381089-83-2.