Tirzepatide
A dual GIP and GLP-1 receptor agonist studied for incretin-pathway signaling and metabolic regulation.
01At a Glance
| Compound | Tirzepatide |
| Also known as | LY3298176 |
| CAS Number | 2023788-19-2 |
| Molecular Weight | 4,813.45 g/mol |
| Sequence / Form | Synthetic 39-aa dual-incretin agonist |
| Classification | Metabolic research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
Tirzepatide is a synthetic 39-amino-acid peptide engineered as a dual agonist of the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. In research models it is studied for the combined activation of both incretin pathways and downstream effects on insulin secretion, glucose homeostasis, and energy metabolism.
Its dual-receptor mechanism is the principal distinction from single GLP-1 agonists, making it a key reference compound in comparative incretin and metabolic-pathway research.
03Research Applications
- 01GIP and GLP-1 receptor co-activation assays
- 02Insulin-secretion and glucose-homeostasis models
- 03Energy-metabolism and adipose research
- 04Comparative incretin-agonist studies
04Purity & Verification
Every Ethos Bio lot of Tirzepatide is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the Tirzepatide Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is Tirzepatide?
Tirzepatide is a synthetic dual GIP/GLP-1 receptor agonist studied for incretin signaling and metabolic regulation in research models. It is sold for research use only and is not for human consumption.
How is Tirzepatide different from Semaglutide?
Tirzepatide activates both the GIP and GLP-1 receptors (dual agonist), while Semaglutide targets only the GLP-1 receptor. The dual mechanism is the focus of comparative metabolic research.
What is the molecular weight of Tirzepatide?
Tirzepatide has a molecular weight of approximately 4,813.45 g/mol and CAS number 2023788-19-2.