Research Library · Mitochondrial

What Is AICAR?

An AMPK-activating nucleoside studied as a metabolic and exercise-mimetic tool.

Class MitochondrialMW 258.23 g/molResearch Use Only

01Definition

AICAR is a mitochondrial research compound. An AMPK-activating nucleoside studied as a metabolic and exercise-mimetic tool. It is also known as Acadesine; AICA riboside.

Sequence · Nucleoside (non-peptide)

02Research Mechanism

AICAR is a nucleoside that is converted intracellularly to ZMP, an AMP mimetic that directly activates AMP-activated protein kinase (AMPK). Through AMPK it is studied for effects on glucose uptake (GLUT4 translocation), fatty-acid oxidation, and mitochondrial biogenesis (PGC-1α).

Research framing only · No human-use claims

03Key Facts

ClassificationMitochondrial
Molecular weight258.23 g/mol
Also known asAcadesine; AICA riboside
Purity spec≥99% HPLC
VerificationMZ Biolabs · 5-panel
UseResearch Use Only

04FAQ

What is AICAR?

AICAR is a mitochondrial research compound. An AMPK-activating nucleoside studied as a metabolic and exercise-mimetic tool. It is also known as Acadesine; AICA riboside. It is supplied strictly for laboratory research use.

What class of compound is AICAR?

AICAR is categorized as Mitochondrial and is studied alongside related compounds in that research area.

What is the molecular weight of AICAR?

AICAR has a molecular weight of 258.23 g/mol.

How is AICAR tested?

Every Ethos Bio lot of AICAR is analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spec identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis.

View AICAR product → · Full monograph → · Molecular weight →