Catalog · Immune

LL-37

Name: LL-37 Research Peptide
Brand: Ethos Bio
Price: 99.99 USD
Availability: InStock

CAS 154947-66-7MW 4,493.3 g/mol≥99.0% Purity

The human cathelicidin antimicrobial peptide studied for membrane interaction and innate immunity.

Quantity per vial

Vials

$99.99

Free cold-chain shipping over $200
Signed COA included with every vial
Batch-pinned ordering for protocol continuity

Research Use Only. Sold for research and identification purposes only. Not intended for human dosing, injection, or ingestion.

Mass-Spec Verified

HPLC + LC-MS per batch at Janoshik.

99% Purity Threshold

Below-spec lots are destroyed, not sold.

Cold-Chain 2–8°C

Continuous transit temperature logging.

U.S. cGMP Compounded

Domestic manufacturing, lot traceability.

Mechanism of action

LL-37 is the only human cathelicidin-derived antimicrobial peptide, a 37-residue amphipathic α-helix. Its primary research property is interaction with and disruption of microbial membranes, the basis of its antimicrobial activity in vitro.

Beyond direct antimicrobial action, it is studied for immunomodulatory roles — chemotaxis, modulation of innate-immune signaling, and angiogenesis — in research models.

Full research overview, applications & FAQ →

Specifications

Compound name	LL-37 (Cathelicidin antimicrobial peptide; CAP-18)
CAS number	154947-66-7
Sequence / Form	37-aa cathelicidin fragment
Molecular weight	4,493.3 g/mol
Classification	Immune research compound
Purity (HPLC)	≥ 99.0%
Identity verification	LC-MS (Janoshik Analytical)
Appearance	White lyophilized powder
Storage	Lyophilized: 2–8°C, sealed. Long-term: −20°C.
Vial sizes	5 mg
Synthesis method	Solid-phase peptide synthesis (SPPS)

Per-lot certificate of analysis

Every shipment of LL-37 includes a signed Certificate of Analysis specific to the lot you receive, documenting HPLC purity, LC-MS identity confirmation, water content, and the cold-chain temperature log. Testing is performed by our independent partner, Janoshik Analytical.

View Certificate of Analysis →

Research Use Only — required disclosure

LL-37, like all Ethos Bio products, is sold strictly for in-vitro and laboratory research use only. It is not a drug, food, cosmetic, or supplement; not intended for human or veterinary consumption; and not intended for the diagnosis, treatment, cure, mitigation, or prevention of any disease.

Sale is restricted to qualified researchers and institutions, aged 21+. By placing an order you certify the compound will be used solely for laboratory research consistent with 21 CFR § 201.128.