Catalog · Regenerative

TB-500

Name: TB-500 Research Peptide
Brand: Ethos Bio
Price: 64.99 USD
Availability: InStock

CAS 77591-33-4MW 4,963.4 g/mol≥99.0% Purity

A synthetic fragment of Thymosin β-4 studied for actin regulation and cell migration.

Quantity per vial

Vials

$64.99

Free cold-chain shipping over $200
Signed COA included with every vial
Batch-pinned ordering for protocol continuity

Research Use Only. Sold for research and identification purposes only. Not intended for human dosing, injection, or ingestion.

Mass-Spec Verified

HPLC + LC-MS per batch at Janoshik.

99% Purity Threshold

Below-spec lots are destroyed, not sold.

Cold-Chain 2–8°C

Continuous transit temperature logging.

U.S. cGMP Compounded

Domestic manufacturing, lot traceability.

Mechanism of action

TB-500 corresponds to the active region of Thymosin β-4, a naturally occurring actin-sequestering protein. Its central LKKTETQ motif binds G-actin, and in research models it is studied for its influence on actin polymerization, cytoskeletal organization, and directed cell migration toward sites of injury.

Published investigations also examine downstream effects on angiogenesis and endothelial migration. All study contexts are in-vitro or animal-model based.

Full research overview, applications & FAQ →

Specifications

Compound name	TB-500 (Thymosin β-4 fragment)
CAS number	77591-33-4
Sequence / Form	Contains the LKKTETQ actin-binding motif
Molecular weight	4,963.4 g/mol
Classification	Regenerative research compound
Purity (HPLC)	≥ 99.0%
Identity verification	LC-MS (Janoshik Analytical)
Appearance	White lyophilized powder
Storage	Lyophilized: 2–8°C, sealed. Long-term: −20°C.
Vial sizes	5 mg · 10 mg
Synthesis method	Solid-phase peptide synthesis (SPPS)

Per-lot certificate of analysis

Every shipment of TB-500 includes a signed Certificate of Analysis specific to the lot you receive, documenting HPLC purity, LC-MS identity confirmation, water content, and the cold-chain temperature log. Testing is performed by our independent partner, Janoshik Analytical.

View Certificate of Analysis →

Research Use Only — required disclosure

TB-500, like all Ethos Bio products, is sold strictly for in-vitro and laboratory research use only. It is not a drug, food, cosmetic, or supplement; not intended for human or veterinary consumption; and not intended for the diagnosis, treatment, cure, mitigation, or prevention of any disease.

Sale is restricted to qualified researchers and institutions, aged 21+. By placing an order you certify the compound will be used solely for laboratory research consistent with 21 CFR § 201.128.