Catalog · Mitochondrial

MOTS-c

Name: MOTS-c Research Peptide
Brand: Ethos Bio
Price: 94.99 USD
Availability: InStock

CAS 1627580-64-6MW 2,174.4 g/mol≥99.0% Purity

A mitochondrial-derived peptide studied for AMPK activation and metabolic regulation.

Quantity per vial

Vials

$94.99

Free cold-chain shipping over $200
Signed COA included with every vial
Batch-pinned ordering for protocol continuity

Research Use Only. Sold for research and identification purposes only. Not intended for human dosing, injection, or ingestion.

Mass-Spec Verified

HPLC + LC-MS per batch at Janoshik.

99% Purity Threshold

Below-spec lots are destroyed, not sold.

Cold-Chain 2–8°C

Continuous transit temperature logging.

U.S. cGMP Compounded

Domestic manufacturing, lot traceability.

Mechanism of action

MOTS-c is a peptide encoded within the mitochondrial 12S rRNA gene. Its central research property is activation of the AMPK energy-sensing pathway, linking it to cellular metabolic homeostasis and the folate–AICAR–de novo purine biosynthesis axis.

Under metabolic stress, studies report nuclear translocation of MOTS-c where it influences stress-adaptive gene expression. It is investigated in metabolic and mitochondrial-biogenesis models only.

Full research overview, applications & FAQ →

Specifications

Compound name	MOTS-c (Mitochondrial ORF of the 12S rRNA type-c)
CAS number	1627580-64-6
Sequence / Form	Mitochondrial-derived 16-aa peptide
Molecular weight	2,174.4 g/mol
Classification	Mitochondrial research compound
Purity (HPLC)	≥ 99.0%
Identity verification	LC-MS (Janoshik Analytical)
Appearance	White lyophilized powder
Storage	Lyophilized: 2–8°C, sealed. Long-term: −20°C.
Vial sizes	10 mg
Synthesis method	Solid-phase peptide synthesis (SPPS)

Per-lot certificate of analysis

Every shipment of MOTS-c includes a signed Certificate of Analysis specific to the lot you receive, documenting HPLC purity, LC-MS identity confirmation, water content, and the cold-chain temperature log. Testing is performed by our independent partner, Janoshik Analytical.

View Certificate of Analysis →

Research Use Only — required disclosure

MOTS-c, like all Ethos Bio products, is sold strictly for in-vitro and laboratory research use only. It is not a drug, food, cosmetic, or supplement; not intended for human or veterinary consumption; and not intended for the diagnosis, treatment, cure, mitigation, or prevention of any disease.

Sale is restricted to qualified researchers and institutions, aged 21+. By placing an order you certify the compound will be used solely for laboratory research consistent with 21 CFR § 201.128.