MOTS-c
A mitochondrial-derived peptide studied for AMPK activation and metabolic regulation.
Research Overview
MOTS-c is a peptide encoded within the mitochondrial 12S rRNA gene. Its central research property is activation of the AMPK energy-sensing pathway, linking it to cellular metabolic homeostasis and the folate–AICAR–de novo purine biosynthesis axis.
Under metabolic stress, studies report nuclear translocation of MOTS-c where it influences stress-adaptive gene expression. It is investigated in metabolic and mitochondrial-biogenesis models only.
Specifications
| Compound | MOTS-c (Mitochondrial ORF of the 12S rRNA type-c) |
| Classification | Mitochondrial research compound |
| Molecular weight | 2,174.4 g/mol |
| Sequence / Form | Mitochondrial-derived 16-aa peptide |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
Quality Documentation
Every released lot is supported by quality-control documentation. Certificate access is presented by compound and lot where available. Cold-chain shipping is available where required; inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
Research Use Only
This product is offered strictly for laboratory research use. It is not a drug, food, cosmetic, supplement, or consumer product, and is not intended for human or veterinary use.
