01At a Glance
| Compound | MTP (Elamipretide; MTP-131) |
| Classification | Mitochondrial research compound |
| Molecular weight | 639.79 g/mol |
| Sequence / Form | D-Arg-2,6-dimethylTyr-Lys-Phe-NH2 |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
MTP is a cell-permeable, mitochondria-targeting tetrapeptide that concentrates on the inner mitochondrial membrane, where it selectively binds the phospholipid cardiolipin. Research models report that this interaction stabilizes cristae architecture and supports efficient electron transport.
By preserving membrane organization it is studied for its capacity to reduce reactive-oxygen-species (ROS) generation and protect mitochondrial bioenergetics.
Research framing only · No human-use claims
03Research Context
- Cardiolipin-binding and inner-membrane assays
- Mitochondrial bioenergetics and cristae-architecture research
- Reactive-oxygen-species (ROS) reduction models
- Cardiac and neuronal mitochondrial-stress studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is MTP?
MTP (elamipretide) is a mitochondria-targeted tetrapeptide studied for binding cardiolipin on the inner mitochondrial membrane, stabilizing cristae and reducing ROS in research models. It is sold for research use only.
What does MTP bind to?
MTP selectively binds cardiolipin, a phospholipid of the inner mitochondrial membrane central to electron-transport-chain organization.
What is MTP's molecular weight?
MTP has a molecular weight of approximately 639.79 g/mol and CAS number 736992-21-5.
How should MTP be stored?
MTP ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is MTP approved for human use?
No. MTP is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is MTP tested at Ethos Bio?
Every MTP lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.