Sermorelin
A GHRH(1-29) analog studied for pituitary growth-hormone stimulation.
01At a Glance
| Compound | Sermorelin |
| Also known as | GRF 1-29 |
| CAS Number | 86168-78-7 |
| Molecular Weight | 3,357.9 g/mol |
| Sequence / Form | GHRH(1-29) |
| Classification | Endocrine research compound |
| Appearance | Lyophilized powder |
| Purity | ≥99% (HPLC · MS-verified) |
| Storage | 2–8°C; -20°C for long-term |
| Intended Use | Research Use Only |
02Mechanism of Action
Sermorelin corresponds to the first 29 amino acids of growth-hormone-releasing hormone — the minimal fully active GHRH fragment. It is studied as a GHRH-receptor agonist that stimulates endogenous growth-hormone synthesis and release from the anterior pituitary.
As a GHRH analog it is a common reference tool in GH-axis and pituitary-secretion research.
03Research Applications
- 01GHRH-receptor agonism assays
- 02Pituitary growth-hormone-secretion models
- 03GH–IGF-1 endocrine-axis research
- 04GHRH-analog comparison studies
04Purity & Verification
Every Ethos Bio lot of Sermorelin is analyzed by reverse-phase HPLC and independently confirmed by mass spectrometry through our third-party testing partner, Janoshik Analytical. A signed Certificate of Analysis documenting identity and ≥99% purity is provided for every lot.
View the Sermorelin Certificate of Analysis
Independent third-party HPLC & mass-spec verification. The COA shipped with your order reflects your specific lot.
05Frequently Asked Questions
What is Sermorelin?
Sermorelin is a GHRH(1-29) analog — the active fragment of growth-hormone-releasing hormone — studied for pituitary GH stimulation in research models. It is a research-use-only compound.
How does Sermorelin compare to CJC-1295?
Both are GHRH-receptor agonists; Sermorelin is the native GHRH(1-29) sequence, while CJC-1295 carries stabilizing modifications studied for extended activity.
What is Sermorelin's molecular weight?
Sermorelin has an approximate molecular weight of 3,357.9 g/mol and CAS number 86168-78-7.