Thymosin Alpha-1
A thymic peptide studied for T-cell maturation and Toll-like-receptor signaling.

01At a Glance
| Compound | Thymosin Alpha-1 (Tα1; Thymalfasin) |
| Classification | Immune research compound |
| Molecular weight | 3,108.3 g/mol |
| Sequence / Form | 28-aa thymic peptide (N-acetylated) |
| Purity | ≥99% HPLC, identity verified by mass spectrometry |
| Documentation | Batch-specific Certificate of Analysis available |
| Appearance | White lyophilized powder |
| Storage | Store sealed at 2–8°C. Long-term storage per certificate guidance. |
| Use | Research Use Only. Not for human or veterinary use. |
02Mechanism of Action
Thymosin Alpha-1 is a 28-amino-acid N-terminally acetylated peptide derived from the thymic protein prothymosin alpha. Research focuses on its role in T-cell maturation and differentiation and modulation of Toll-like receptors (TLR2, TLR9) on dendritic cells.
It is studied as an immune-modulating tool that influences Th1 responses in immunological assays.
Research framing only · No human-use claims
03Research Context
- T-cell maturation and differentiation assays
- Toll-like-receptor (TLR2/TLR9) signaling research
- Dendritic-cell and Th1-response models
- Antiviral and immune-modulation studies
04Quality & Verification
Ethos Bio presents compound information with an emphasis on identity verification, purity analysis, certificate access, and storage guidance. Product-specific documentation is available through the certificate page where applicable. Cold-chain shipping is available where required, and inventory is held under refrigerated conditions at our fulfillment center with temperature-logging protocols in place.
05FAQ
What is Thymosin Alpha-1?
Thymosin Alpha-1 is a 28-amino-acid thymic peptide studied for T-cell maturation and Toll-like-receptor signaling in immune research models. It is sold for research use only.
What pathways does Thymosin Alpha-1 modulate?
In research models it is associated with Toll-like receptor (TLR2/TLR9) signaling and T-cell differentiation toward Th1 immune responses.
What is Thymosin Alpha-1's molecular weight?
Thymosin Alpha-1 has an approximate molecular weight of 3,108.3 g/mol and CAS number 62304-98-7.
How should Thymosin Alpha-1 be stored?
Thymosin Alpha-1 ships lyophilized and should be handled per standard research-peptide practice — kept cold, protected from light and moisture, and reconstituted only for laboratory use. Cold-chain handling is used where required. For research use only.
Is Thymosin Alpha-1 approved for human use?
No. Thymosin Alpha-1 is sold strictly for laboratory research use only and is not a drug or supplement. It is not approved for human or veterinary use or consumption.
How is Thymosin Alpha-1 tested at Ethos Bio?
Every Thymosin Alpha-1 lot is independently verified by MZ Biolabs, a third-party analytical laboratory in Arizona, on a five-point panel — RP-HPLC purity, HPLC-MS identity, endotoxin (LAL), heavy metals, and sterility. A lot-specific certificate of analysis ships with the vial. See How We Test for the full methodology.