What Is MOTS-c?
A mitochondrial-derived peptide studied for AMPK activation and metabolic regulation.
01Definition
MOTS-c is a mitochondrial research compound. A mitochondrial-derived peptide studied for AMPK activation and metabolic regulation. It is also known as Mitochondrial ORF of the 12S rRNA type-c.
Sequence · Mitochondrial-derived 16-aa peptide
02Research Mechanism
MOTS-c is a peptide encoded within the mitochondrial 12S rRNA gene. Its central research property is activation of the AMPK energy-sensing pathway, linking it to cellular metabolic homeostasis and the folate–AICAR–de novo purine biosynthesis axis.
Research framing only · No human-use claims
03Key Facts
| Classification | Mitochondrial |
| Molecular weight | 2,174.4 g/mol |
| Also known as | Mitochondrial ORF of the 12S rRNA type-c |
| Purity spec | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel |
| Use | Research Use Only |
04FAQ
What is MOTS-c?
MOTS-c is a mitochondrial research compound. A mitochondrial-derived peptide studied for AMPK activation and metabolic regulation. It is also known as Mitochondrial ORF of the 12S rRNA type-c. It is supplied strictly for laboratory research use.
What class of compound is MOTS-c?
MOTS-c is categorized as Mitochondrial and is studied alongside related compounds in that research area.
What is the molecular weight of MOTS-c?
MOTS-c has a molecular weight of 2,174.4 g/mol.
How is MOTS-c tested?
Every Ethos Bio lot of MOTS-c is analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spec identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis.
View MOTS-c product → · Full monograph → · Molecular weight →