BPC-157 vs ARA-290
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| BPC-157 | ARA-290 | |
|---|---|---|
| Classification | Regenerative | Regenerative |
| Molecular weight | 1,419.5 g/mol | 1,258.42 g/mol |
| Also known as | Body Protection Compound 157; PL 14736 | Cibinetide |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
BPC-157
A synthetic gastric pentadecapeptide widely studied for angiogenic and cytoprotective signaling.
BPC-157 is a stable 15-amino-acid sequence derived from a protective protein found in human gastric juice. In research models it is most associated with the VEGFR2–Akt–eNOS signaling axis, where it has been reported to upregulate vascular endothelial growth factor receptor 2 and promote angiogenesis in endothelial cell assays.
ARA-290
An erythropoietin-derived peptide studied for innate-repair-receptor signaling.
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from the helix-B region of erythropoietin. It is studied as a selective agonist of the innate repair receptor — a heterocomplex of the EPO receptor and the β-common receptor (CD131) — associated with tissue protection and anti-inflammatory signaling.
Research framing only · No human-use claims
03Selecting for a Research Model
Because BPC-157 and ARA-290 are both regenerative research compounds, they are frequently evaluated against one another. Selection depends on the research question, model system, and endpoints. Both are supplied strictly for laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between BPC-157 and ARA-290?
BPC-157 is a regenerative research compound — A synthetic gastric pentadecapeptide widely studied for angiogenic and cytoprotective signaling. ARA-290 is also studied within the regenerative area — An erythropoietin-derived peptide studied for innate-repair-receptor signaling. They differ in molecular weight (BPC-157: 1,419.5 g/mol; ARA-290: 1,258.42 g/mol). Both are for laboratory research use only.
What are the molecular weights of BPC-157 and ARA-290?
BPC-157: 1,419.5 g/mol. ARA-290: 1,258.42 g/mol.
Are BPC-157 and ARA-290 in the same research class?
Yes — both are categorized as Regenerative research compounds.
How are BPC-157 and ARA-290 tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spec identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis per lot.