IGF-1 LR3 vs PEG-MGF
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| IGF-1 LR3 | PEG-MGF | |
|---|---|---|
| Classification | Endocrine | Endocrine |
| Molecular weight | 9,117.7 g/mol | — (PEGylated) |
| Also known as | Long R3 IGF-1 | Pegylated Mechano Growth Factor |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
IGF-1 LR3
A long-acting IGF-1 analog studied for IGF-1R signaling and cell proliferation.
IGF-1 LR3 is an 83-amino-acid analog of insulin-like growth factor 1, modified with an Arg substitution at position 3 and an N-terminal extension that reduces binding to IGF-binding proteins, prolonging its activity in research systems.
PEG-MGF
A PEGylated IGF-1 splice variant studied for satellite-cell proliferation pathways.
PEG-MGF is a PEGylated form of mechano growth factor (MGF), a splice variant of IGF-1 (IGF-1Ec) produced in response to mechanical stress. The PEGylation extends stability in research systems.
Research framing only · No human-use claims
03Selecting for a Research Model
Because IGF-1 LR3 and PEG-MGF are both endocrine research compounds, they are frequently evaluated against one another. Selection depends on the research question, model system, and endpoints. Both are supplied strictly for laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between IGF-1 LR3 and PEG-MGF?
IGF-1 LR3 is a endocrine research compound — A long-acting IGF-1 analog studied for IGF-1R signaling and cell proliferation. PEG-MGF is also studied within the endocrine area — A PEGylated IGF-1 splice variant studied for satellite-cell proliferation pathways. They differ in molecular weight (IGF-1 LR3: 9,117.7 g/mol; PEG-MGF: — (PEGylated)). Both are for laboratory research use only.
What are the molecular weights of IGF-1 LR3 and PEG-MGF?
IGF-1 LR3: 9,117.7 g/mol. PEG-MGF: — (PEGylated).
Are IGF-1 LR3 and PEG-MGF in the same research class?
Yes — both are categorized as Endocrine research compounds.
How are IGF-1 LR3 and PEG-MGF tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spec identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis per lot.