KPV vs ARA-290
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| KPV | ARA-290 | |
|---|---|---|
| Classification | Regenerative | Regenerative |
| Molecular weight | 410.51 g/mol | 1,258.42 g/mol |
| Also known as | α-MSH(11-13) | Cibinetide |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
KPV
The C-terminal α-MSH tripeptide studied for NF-κB and inflammatory-signaling modulation.
KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone. Research focuses on its inhibition of NF-κB signaling and reduction of pro-inflammatory cytokine expression in cell models.
ARA-290
An erythropoietin-derived peptide studied for innate-repair-receptor signaling.
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from the helix-B region of erythropoietin. It is studied as a selective agonist of the innate repair receptor — a heterocomplex of the EPO receptor and the β-common receptor (CD131) — associated with tissue protection and anti-inflammatory signaling.
Research framing only · No human-use claims
03Selecting for a Research Model
Because KPV and ARA-290 are both regenerative research compounds, they are frequently evaluated against one another. Selection depends entirely on the research question, model system, and endpoints being measured. Both compounds are supplied strictly for in-vitro and laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between KPV and ARA-290?
KPV is a regenerative research compound — The C-terminal α-MSH tripeptide studied for NF-κB and inflammatory-signaling modulation. ARA-290 is also studied within the regenerative area — An erythropoietin-derived peptide studied for innate-repair-receptor signaling. They differ in molecular weight (KPV: 410.51 g/mol; ARA-290: 1,258.42 g/mol) and primary mechanism. Both are supplied for laboratory research use only.
What are the molecular weights of KPV and ARA-290?
KPV has a molecular weight of 410.51 g/mol. ARA-290 has a molecular weight of 1,258.42 g/mol.
Are KPV and ARA-290 in the same research class?
Yes — both KPV and ARA-290 are categorized as Regenerative research compounds, which is why they are often compared.
How are KPV and ARA-290 tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spectrometry identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis provided per lot.