NAD+ vs 5-Amino-1MQ
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| NAD+ | 5-Amino-1MQ | |
|---|---|---|
| Classification | Mitochondrial | Mitochondrial |
| Molecular weight | 663.43 g/mol | 159.21 g/mol |
| Also known as | Nicotinamide adenine dinucleotide | 5-amino-1-methylquinolinium |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
NAD+
An essential redox coenzyme and sirtuin cofactor central to cellular energy research.
NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme in redox reactions, cycling between NAD+ and NADH to shuttle electrons through central metabolism. It is the rate-limiting cofactor for the sirtuin family (SIRT1–7) of deacetylases studied in cellular-aging research.
5-Amino-1MQ
A small-molecule NNMT inhibitor studied for NAD+ salvage and adipocyte metabolism.
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide. By inhibiting NNMT, research models report increased availability of nicotinamide for NAD+ salvage and altered S-adenosylmethionine (SAM) flux.
Research framing only · No human-use claims
03Selecting for a Research Model
Because NAD+ and 5-Amino-1MQ are both mitochondrial research compounds, they are frequently evaluated against one another. Selection depends entirely on the research question, model system, and endpoints being measured. Both compounds are supplied strictly for in-vitro and laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between NAD+ and 5-Amino-1MQ?
NAD+ is a mitochondrial research compound — An essential redox coenzyme and sirtuin cofactor central to cellular energy research. 5-Amino-1MQ is also studied within the mitochondrial area — A small-molecule NNMT inhibitor studied for NAD+ salvage and adipocyte metabolism. They differ in molecular weight (NAD+: 663.43 g/mol; 5-Amino-1MQ: 159.21 g/mol) and primary mechanism. Both are supplied for laboratory research use only.
What are the molecular weights of NAD+ and 5-Amino-1MQ?
NAD+ has a molecular weight of 663.43 g/mol. 5-Amino-1MQ has a molecular weight of 159.21 g/mol.
Are NAD+ and 5-Amino-1MQ in the same research class?
Yes — both NAD+ and 5-Amino-1MQ are categorized as Mitochondrial research compounds, which is why they are often compared.
How are NAD+ and 5-Amino-1MQ tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spectrometry identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis provided per lot.