Sermorelin vs Ipamorelin
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| Sermorelin | Ipamorelin | |
|---|---|---|
| Classification | Endocrine | Endocrine |
| Molecular weight | 3,357.9 g/mol | 711.85 g/mol |
| Also known as | GRF 1-29 | NNC 26-0161 |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
Sermorelin
A GHRH(1-29) analog studied for pituitary growth-hormone stimulation.
Sermorelin corresponds to the first 29 amino acids of growth-hormone-releasing hormone — the minimal fully active GHRH fragment. It is studied as a GHRH-receptor agonist that stimulates endogenous growth-hormone synthesis and release from the anterior pituitary.
Ipamorelin
A selective ghrelin-receptor agonist studied for clean growth-hormone secretagogue activity.
Ipamorelin is a synthetic pentapeptide and selective agonist of the ghrelin receptor (GHS-R1a). In research models it stimulates growth-hormone release from the pituitary with notable selectivity — published work emphasizes minimal effect on prolactin, cortisol, and ACTH compared with earlier secretagogues.
Research framing only · No human-use claims
03Selecting for a Research Model
Because Sermorelin and Ipamorelin are both endocrine research compounds, they are frequently evaluated against one another. Selection depends on the research question, model system, and endpoints. Both are supplied strictly for laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between Sermorelin and Ipamorelin?
Sermorelin is a endocrine research compound — A GHRH(1-29) analog studied for pituitary growth-hormone stimulation. Ipamorelin is also studied within the endocrine area — A selective ghrelin-receptor agonist studied for clean growth-hormone secretagogue activity. They differ in molecular weight (Sermorelin: 3,357.9 g/mol; Ipamorelin: 711.85 g/mol). Both are for laboratory research use only.
What are the molecular weights of Sermorelin and Ipamorelin?
Sermorelin: 3,357.9 g/mol. Ipamorelin: 711.85 g/mol.
Are Sermorelin and Ipamorelin in the same research class?
Yes — both are categorized as Endocrine research compounds.
How are Sermorelin and Ipamorelin tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spec identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis per lot.