Sermorelin vs Tesamorelin
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| Sermorelin | Tesamorelin | |
|---|---|---|
| Classification | Endocrine | Endocrine |
| Molecular weight | 3,357.9 g/mol | 5,135.9 g/mol |
| Also known as | GRF 1-29 | TH9507 |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
Sermorelin
A GHRH(1-29) analog studied for pituitary growth-hormone stimulation.
Sermorelin corresponds to the first 29 amino acids of growth-hormone-releasing hormone — the minimal fully active GHRH fragment. It is studied as a GHRH-receptor agonist that stimulates endogenous growth-hormone synthesis and release from the anterior pituitary.
Tesamorelin
A stabilized GHRH(1-44) analog studied for growth-hormone-axis and lipid metabolism.
Tesamorelin is a stabilized analog of the full-length growth-hormone-releasing hormone GHRH(1-44). As a GHRH-receptor agonist it is studied for stimulation of endogenous growth-hormone secretion and downstream IGF-1 signaling.
Research framing only · No human-use claims
03Selecting for a Research Model
Because Sermorelin and Tesamorelin are both endocrine research compounds, they are frequently evaluated against one another. Selection depends entirely on the research question, model system, and endpoints being measured. Both compounds are supplied strictly for in-vitro and laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between Sermorelin and Tesamorelin?
Sermorelin is a endocrine research compound — A GHRH(1-29) analog studied for pituitary growth-hormone stimulation. Tesamorelin is also studied within the endocrine area — A stabilized GHRH(1-44) analog studied for growth-hormone-axis and lipid metabolism. They differ in molecular weight (Sermorelin: 3,357.9 g/mol; Tesamorelin: 5,135.9 g/mol) and primary mechanism. Both are supplied for laboratory research use only.
What are the molecular weights of Sermorelin and Tesamorelin?
Sermorelin has a molecular weight of 3,357.9 g/mol. Tesamorelin has a molecular weight of 5,135.9 g/mol.
Are Sermorelin and Tesamorelin in the same research class?
Yes — both Sermorelin and Tesamorelin are categorized as Endocrine research compounds, which is why they are often compared.
How are Sermorelin and Tesamorelin tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spectrometry identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis provided per lot.