TB-500 vs KPV
A side-by-side research comparison — classification, molecular weight, mechanism, and how each is verified. For laboratory research use only.
01At a Glance
| TB-500 | KPV | |
|---|---|---|
| Classification | Regenerative | Regenerative |
| Molecular weight | 4,963.4 g/mol | 410.51 g/mol |
| Also known as | Thymosin β-4 fragment | α-MSH(11-13) |
| Purity spec | ≥99% HPLC | ≥99% HPLC |
| Verification | MZ Biolabs · 5-panel | MZ Biolabs · 5-panel |
| Use | Research Use Only | Research Use Only |
02How They Differ
TB-500
A synthetic fragment of Thymosin β-4 studied for actin regulation and cell migration.
TB-500 corresponds to the active region of Thymosin β-4, a naturally occurring actin-sequestering protein. Its central LKKTETQ motif binds G-actin, and in research models it is studied for its influence on actin polymerization, cytoskeletal organization, and directed cell migration toward sites of injury.
KPV
The C-terminal α-MSH tripeptide studied for NF-κB and inflammatory-signaling modulation.
KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone. Research focuses on its inhibition of NF-κB signaling and reduction of pro-inflammatory cytokine expression in cell models.
Research framing only · No human-use claims
03Selecting for a Research Model
Because TB-500 and KPV are both regenerative research compounds, they are frequently evaluated against one another. Selection depends on the research question, model system, and endpoints. Both are supplied strictly for laboratory research and are not for human or veterinary use.
Whichever you select, every Ethos Bio lot is verified the same way — a five-point independent panel with a batch-specific Certificate of Analysis. See how we test →
04FAQ
What is the difference between TB-500 and KPV?
TB-500 is a regenerative research compound — A synthetic fragment of Thymosin β-4 studied for actin regulation and cell migration. KPV is also studied within the regenerative area — The C-terminal α-MSH tripeptide studied for NF-κB and inflammatory-signaling modulation. They differ in molecular weight (TB-500: 4,963.4 g/mol; KPV: 410.51 g/mol). Both are for laboratory research use only.
What are the molecular weights of TB-500 and KPV?
TB-500: 4,963.4 g/mol. KPV: 410.51 g/mol.
Are TB-500 and KPV in the same research class?
Yes — both are categorized as Regenerative research compounds.
How are TB-500 and KPV tested?
Both are analyzed by an independent third-party laboratory (MZ Biolabs, Arizona) on a five-point panel — HPLC purity, mass-spec identity, endotoxin, heavy metals, and sterility — with a batch-specific Certificate of Analysis per lot.